Regulation, low risk appetite drag on trading: Saxo Bank

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He blamed tougher capital requirements at banks and new limits on the ability of its clients to gear their positions by borrowing against assets. ...","sUltBucketId":"test1","sUltSection":"sentirating","sUltBeaconUrl":"","sUltRecordPageviews":"1","sUltBeaconEnable":"1","serviceUrl":"\/_xhr","publisherContextId":"","propertyId":"2fcd79b5-b3a3-333e-b98e-722536a6698f","configurationId":"435db9ee-c55e-3766-b20d-c8ad3ff889d1","graphId":"","labelLeft":"Not at all confident","labelRight":"Completely confident","labelMiddle":"","itemimg":"http:\/\/l.yimg.com\/a\/i\/ww\/met\/yahoo_logo_us_061509.png","selfURI":"","aggregateRatingCount":"1085","aggregateReviewCount":"0","leftBlocksNum":"1036","rightBlocksNum":"49","leftBlocksPerCent":"95","rightBlocksPerCent":"5","ugcrate_apihost":"api01-us.ugcl.yahoo.com:4080","publisher_id":"news-en-US","yca_cert":"yahoo.ugccloud.app.trusted_proxies","timeout_write":"5000","through_proxy":"false","optionStats":"{\"s1\":847,\"s2\":70,\"s3\":44,\"s4\":39,\"s5\":36,\"s6\":49,\"s7\":0,\"s8\":0,\"s9\":0,\"s10\":0}","l10N":"{\"FIRST_TO_READ\":\"You are first to read this. 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Source: http://news.yahoo.com/regulation-low-risk-appetite-drag-trading-saxo-bank-145032756--sector.html

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New chemistry technique reproduces nature's elusive complexity

ScienceDaily (Sep. 23, 2012) ? Scientists at The Scripps Research Institute have shown how to synthesize in the laboratory an important set of natural compounds known as terpenes. The largest class of chemicals made by living organisms, terpenes are made within cells by some of the most complex chemical reactions found in biology.

The new technique, described in an advance online edition of the journal Nature Chemistry on Sept. 23, 2012, mimics a crucial but obscure biochemical phenomenon that allows cells to make terpenes. The discovery may one day result in cheaper, fully synthetic versions of the cancer drug Taxol, the antimalarial compound artemisinin and hundreds of other useful terpene products.

"It's exciting for us because we're now making molecules that have never been made in the laboratory before, and we've done this by first observing what nature does," said the senior investigator for the study Ryan A. Shenvi, a chemist at Scripps Research.

Powerful Biological Functions

Terpenes take their name from one of their best-known representatives, the paint thinner turpentine -- a derivative of pine sap. Many terpenes, like those in turpentine, are small, plant-made molecules that turn into vapor at relatively low temperatures and waft easily through the air. These often serve as important chemical signals for plants, and are used by humans in fragrances and flavorings.

Some terpenes are more complex, and are synthesized by plants and other organisms as powerful cellular defense mechanisms. "Having such strong biological functions can make them very useful in medicine," said Shenvi. Paclitaxel (Taxol), a widely used cancer drug, is a terpene derived from the bark of the Pacific yew tree. Artemisinin, the basis for a major class of antimalarial therapy, is a terpene made by the sweet wormwood herb. But the terpene family is highly diverse and also includes vitamin A, menthol, cholesterol and steroids.

Many terpenes, including Taxol and artemisinin, are made naturally in cells by processes that are so complicated, and so hard to understand, that chemists haven't been able to recreate them fully using organic chemistry techniques. The commercial production of these two medicines still depends on the relatively expensive harvesting of starting compounds from plants.

Taking Up the Challenge

In the new study, Shenvi and a postdoctoral researcher in his laboratory, Sergey V. Pronin, set out to recreate one of the two major terpene synthesis processes in nature. Known as tail-to-head polycyclization, this process is used by cells to make numerous complex terpenes. (The other major terpene synthesis process, head-to-tail polycyclization, is already partially reproducible with organic chemistry, and results in terpenes that include steroids.)

The tail-to-head polycyclization process begins with a relatively simple chain of carbon atoms, each of which is decorated with other, mostly hydrogen atoms. The goal of the process is to bend this linear hydrocarbon structure in a way that yields one ringlike structure, then another, and so on in a "polycyclic" chain.

A crucial feature of this process is the effective displacement of positive charge from one carbon atom on the structure to another, in just the right sequence. What makes this feat so challenging for chemists to reproduce, and even to analyze, is that this positively charged state in principle can slide along numerous alternative pathways on the emerging structure. Moreover, because it powerfully attracts negatively charged ions, this carbon-based positive charge, which chemists refer to as a carbocation ["carbo-cat-eye-on"], is inclined to snuff itself out almost immediately.

"Carbocations are notoriously tricky to include in synthetic procedures in the laboratory, because their lifetimes are so short," said Shenvi. "And yet nature has evolved tools to handle them."

Chief among these tools are cyclase enzymes, which hold terpene molecules that are under construction and use their own charged structures to protect carbocations from being quenched -- at least long enough to let them do their work. Chemists who have sought to synthesize terpenes in the laboratory generally have done so without trying to mimic these enzymes' charge sequestration mechanism.

"The natural synthetic pathways were assumed to be much too difficult and maybe impossible," Shenvi said. "But we decided that we would have to recreate it somehow if we wanted to develop a broadly useful technique for making this group of terpenes."

Following Nature's Lead

Pronin and Shenvi eventually found that a type of vinyl epoxide seems to serve as a partial substitute for cyclase enzymes. "We think that it effectively holds the negatively charged counteranion, which would otherwise follow and quench the carbocation before the reaction is complete," said Pronin.

As a demonstration of the power of their new technique, the chemists used it to make two different types of terpene, known as funebrene and cumacrene, starting from relatively simple organic chemistry ingredients. These terpene compounds had never before been fully synthesized outside of living cells.

Shenvi emphasizes that this report represents merely an initial, foundational description of this new strategy, and that technical obstacles still prevent its widespread use. "But once we can get past these obstacles, we should be able to use this new approach to fully synthesize many other valuable compounds," he said. "Basically the entire realm of terpenes will be reproducible with organic chemistry."

Funding for the study, "Synthesis of highly strained terpenes by non-stop tail-to-head polycyclization," was provided by a start-up grant from the Scripps Research Institute and a grant from Eli Lilly & Co.

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The above story is reprinted from materials provided by The Scripps Research Institute, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Sergey V. Pronin, Ryan A. Shenvi. Synthesis of highly strained terpenes by non-stop tail-to-head polycyclization. Nature Chemistry, 2012; DOI: 10.1038/NCHEM.1458

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/7iGecnedq_s/120923141822.htm

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Mobile Text Messaging Technology Could Play A Vital Role In ...

Did you know that more than 2 million patients die every year of skin cancer in the United States alone? And, unless you have been hiding under a rock, you must have already felt the effects of global warming and also come across newspaper reports that in 90% of the cases, it is the big bad sun that is to be blamed for skin cancer. So, it goes without mention that every little fruitful effort to reduce the risk of skin cancer in the country counts. Now, what exactly has Mobile text messaging technology got to do with skin cancer?

Well, recently the center for connected health conducted a nationwide study to find out how effective mobile text messaging technology was in increasing awareness about the causative factors of skin cancer and also how sunscreen could protect your skin. It was found that mobile text messaging technology was more effective in reminding people about sunscreen use compared to reminders sent over e-mails and the recall value of print and television advertisements. The Center for connected health found out that mobile text messaging technology was a very low-cost and innovative way of staying connected with hundreds and thousands of cell phone users across the country and this technology could be possibly used even for larger scale health issues. The organization also found out that text messaging was more capable of influencing people into visiting their dermatologists more regularly and calculations by experts revealed that just mobile text messaging technology alone was capable of reducing skin cancer in the country by at least 35%. Now, that is something you cannot ignore. Neither could be mass communication experts ignore the figures.

After a little bit of number crunching it was found that 85% of cell phone users cannot ignore text message on their cell phones. A strange psychology works here ? more than half of all cell phone users in the country wouldn?t mind disconnecting and unwanted call from an unknown number and maybe even the extent of blacklisting it, but when it comes to messages, almost all cell phone users cannot resist the urge to find out what?s written in there. That makes mobile text messaging technology one of the most effective communication technologies ? sometimes it is even better than e-mail.

Experts believe that by using mobile text messaging technology, different government and nongovernment organizations will be able to reach out to a wider section of the demography and create awareness about killer diseases. However, just like any other scientific marvel, mobile text messaging technology also has its own set of disadvantages. According to the recent rules laid down by the United States government, all text messages, especially those that are sent by healthcare organizations and medical professionals need to be HIPPA compliant. This act has been put in place to make sure that the privacy and security of the patients do not get compromised under any circumstance. There have been instances when cell phones got stolen or misplaced and ended up in the wrong hands where they were hacked into and personal information of patients, especially celebrities, were extracted and publicized without the consent of the patient himself. So, the healthcare organizations just need to make sure that all text messages are HIPPA compliant.

Author: This is guest post by Kimber, a technology writer who researches and writes for Hippomsg.com, a private texting app for physicians which is compliant to HIPPA regulations.

Source: http://www.callbox7.com/mobile-text-messaging-technology-could-play-a-vital-role-in-reducing-skin-cancer/

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Jack Harrington, M. Ed. ? EzineArticles.com Expert Author | Online ...

Reference and Education: Future Concepts ? Published: May 1, 2009

Producing Educated & Performing Individuals Experiential education (EE), unfortunately, is not the conventional K12 drill receiving place around the creation today. There are a number of reasons that minister to this set-back and this essay will not casing them. Instead, we?ll concentration on the characteristics of experiential education and its benefits. EE has been around for centuries and newly there appears to be a resurgence of it due to the insufficient dash opening of normal drill methods. EE is a true deliver draw close to learning and is easy to implement; it may be used in any theme area at any rank level.

Source: http://www.isprof.com/jack-harrington-m-ed-ezinearticles-com-expert-author.html

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Update to iOS 6? Sure, but Temper Your Expectations

The astounding thing about the Apple ecosystem of iOS devices for the iPhone, iPad, and iPod is that its users can upgrade relatively easily -- and do -- to the latest and greatest version of Apple's mobile operating system. The upside is that even users on older hardware can get in on some of the new iOS love. The downside? Sometimes that love is mostly just a friendly hug.

Source: http://ectnews.com.feedsportal.com/c/34520/f/632000/s/23c16e44/l/0L0Stechnewsworld0N0Crsstory0C762260Bhtml/story01.htm

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The Record Blogs: The Arts Whisperer: folk music as entertainment ...

There's nothing more pleasing than a happy accident.? On Saturday afternoon?my evening plans went awry.?? Terribly awry and I was left with nothing to do that evening.? Anyone who knows me understands the only thing worse than staying home alone on a Saturday evening is staying home on?Friday and Saturday night on the same weekend.? Since I was home the night before, there was no way I would not go out on this Saturday.

I decided to attend "Four Seasons, Four Years - the Civil War: A Musical Journey."? It was being presented by Caffe Lena at Universal Preservation Hall in Saratoga Springs and the material was produced by Old Songs.??

I am neither a "folkie" nor a Civil War buff, but there is no denying the credentials of those involved with this project.?? An added bonus was the 11 performers who are the cream of local folk artists. It was a brilliant experience that validated my personal axiom that you never can go wrong attending something presented by people who understand and practice quality in their lives and their art.

The premise of the piece created by Andy Spence (the artistic director of Old Songs) is to tell the story of the Civil War using authentic folk songs of the era.?? There is a bit of narration to?set the?background for the song and at other times a letter or other correspondence is read to give a personal voice to?the proceedings.? For the most part the narration is short and to the point.

The result is (depending on your point of view) an entertaining night that is an insightful educational experience or an educational experience that is enormously entertaining.? Either works.

The genius of "Four Season, Four Years" is that because of the authentic music of the era it makes a powerful emotional statement.? We've all read or heard letters written by those involved in the Civil War but the songs in the show represent a more general view of what was going on.? It is not the thought of an individual about a personal experience - the songs (though written by one person) represent the feelings of the population at large.? If it didn't they wouldn't have been performed or survived.

In my mind, this defines the value of any folk art.? It is created specifically for a moment in time and like the music in this piece, clearly expresses to us - 150 years later - the sense of what people were going through - their hopes, dreams. fears and concerns.? It is extremely honest, personal and very revealing.

Enhancing the experience was the interpretive skills of the performers.? There was never the sense that the songs were performed to satisfy the taste of a modern audience.??Because?everyone of the eleven performers on stage are gifted individual artists they attempted to become a person performing the material during the Civil War. In many ways this song cycle was incredible theater.

Though most of the tunes are obscure songs there are a number of familiar songs in the presentation and often it was as if you were hearing them for the first time.? "When Johnny Comes Marching Home" has a rueful tone as it signals the end of a war in which everyone lost something.?In much the same way when the show closes with "Home Sweet Home" the irony is sad and touching. The rendition of"John Brown's Body" begins almost as if a community chant and evolves into a powerful anthem.?

And speaking of anthems, when the performers build the emotions of? the first act ending with "Battle Hymn of the Republic," it is easy to visualize eager young men signing oaths to die for a cause.

The second act tells of those who died for a cause they didn't understand.? While the first segment sets up the political conditions that led to the war, the second half of the show focuses on the pain, suffering and misery the conflict caused for both side.??? If the show could be improved it would be during the second act to offer less detail on every major battle by exploring the the thoughts of the participants.? It might sound callous, but the truth is history has made us almost immune to the suffering of that horrible war.? For example a touching rendition of "Tenting on the Old Campground" - about soldiers retiring for the night after a horrific battle doesn't need a set up.? We get the pain of loss through the music and the lyrics.?? It is beautiful and painful at the same time. And when those emotions come from the music it is powerful.

Indeed, because of the music, I left Universal Preservation Hall thinking about the Civil War in a way I had never done before.?? I really didn't learn too much I didn't know already but I felt touched by the people who lived in that period in a way I never felt before.

The future of "Four Seasons, Four Years - the Civil War: a Musical Journey" is uncertain. It is a work that should not be neglected or discarded.? At the least it should be presented on every area college campus.?? It's an important piece?- musically and historically.??

For information on the show contact Andy Spence at Old Songs, Voorheesville, NY? 765-2815, www.oldsongs.org

Source: http://artswhisperer.blogspot.com/2012/09/folk-music-as-entertainment-and-history.html

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MONEY? News ? Portland Exotic Veterinarian Joins Up With Animal ...

PORTLAND, Ore., Sept. 23, 2012 (GLOBE NEWSWIRE) ? Paws and Claws Pet Medical Center, one of the only Portland animal vet clinics to provide exotic veterinary care, announced the addition of a visiting exotic and avian veterinarian. Dr. Ross Weinstein will be joining the vet center as a temporary visiting veterinarian starting in late September. Dr. Weinstein will be at the veterinary hospital every Monday throughout the month of October. Dr. Weinstein will be assisting the hospital?s veterinarians, Dr. Pollock and Dr. DeRemer, in providing exotic and avian pet care for the Portland East County pet community.

Portland avian veterinarian Dr. Ken DeRemer announced that an additional exotic and avian veterinarian will be temporarily joining Paws and Claws Pet Medical Center. Dr. Ross Weinstein, formerly with the North Portland veterinary hospital, will be assisting in avian and exotic pet care on Mondays, starting September 24, and every Monday in October.

?We are excited to welcome Dr. Weinstein to assist in providing additional exotic vet care,? said Dr. DeRemer. ?Dr. Weinstein is a talented exotic and avian veterinarian and will be a tremendous asset to our veterinary hospital. With Dr. Weinstein?s addition, Paws and Claws will be one of the only Portland exotic veterinarians to have three exotic and avian veterinarians on staff.?

The clinic?s Portland exotic veterinary services include wellness exams, vaccinations, emergency care, and pet surgery. Dr. DeRemer and exotic veterinarian Dr. Pollock see all types of avian and exotic species. Veterinarian Dr. Huntsinger also provides care for pocket pets.

The Gresham exotic veterinary care team recommends regular exams for exotics. According to Dr. DeRemer, many pet owners do not realize that an annual exam is just as important for birds and exotic pets as it is for dogs and cats.

?Owning birds or other exotic pets can be an exciting and rewarding experience,? said Dr. DeRemer. ?Like cats and dogs, exotic pets require regular wellness care to stay healthy. Paws and Claws Pet Medical Center is one of the only Portland veterinary hospitals to provide comprehensive care for exotic animals.?

Exotic services include physicals, diagnostic exams, and nutrition counseling. For example, a fecal exam helps ensure that reptiles, such as iguanas and snakes, are parasite-free.

?Some exotic pets, including reptiles and birds, can live a very long time, while others, such as pocket pets, have a shorter life expectancy,? said Dr. DeRemer. ?Preventative care ensures that a pet?s unique nutrition and habitat needs are met, and that they are free from parasites or diseases.?

In addition to preventative care, the animal hospital provides surgical care and urgent care for exotic and avian pets. The temporary addition of Dr. Weinstein to the exotic veterinarian care team will allow the clinic to provide more appointments and services for exotic pets.

Pet owners may schedule an appointment by calling the hospital or visiting http://pawsandclawsvet.com/.>

Source: http://money.ca/money/2012/09/23/portland-exotic-veterinarian-joins-up-with-animal-hospital-to-provide-additional-exotic-services/

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No glitz for this golden celebration When is a birthday party not a ...

When is a birthday party not a party?

Image via blogspot.com


By Dr. Elinor Garely, Editor in Chief, TourismExecutives.com (a division of eTN Publishing) | Sep 23, 2012

I can answer this question: when a major NYC branded hotel holds a 50th birthday celebration and there is no food, no wine, no spirits and only a small birthday cake served with even smaller bottles of water.

First The Invite
The e-invitation came from the PR representative of a very large NYC hotel (1780 rooms). Celebrating the birthdays of others is one of my favorite things: Count me in!

Hotel Parties are Usually Over-the-Top
I love hotel parties. Chefs, motivated to pull out their best wines and spirits provide dazzling displays; creative culinary treats are stacked on large tables with stiff white cloths; staff members, on their best behavior, wear sparkling clean uniforms or party clothes. Between the balloons, and happy music, hotel parties are frequently the best!

Anticipating a fun-filled afternoon and evening, I turned down a ribbon-cutting ceremony for a new building, a meeting with a colleague, and a dental appointment. I thought about wearing something sparkling with stilettos ? but the event started at 2:00 pm, and I thought it was a bit early for sequins and feathers. Oh yes, another reason to censor an elaborate frock - I was taking the subway (north) from Tribeca.

I Weep from Disappointment
Let me make sure the facts are correct: the invitation was for a 50th birthday party; however, there was no wine/spirits? in fact, there was no beverage bar at all (not a Coke or Diet Pepsi in sight). There were no hors d?oeuvres (not even little frankfurters in pastry blankets). There were no cheese platters, not even cheez-wiz with saltines, not a slice of cold pizza or a stale cookie. There was no food! Has anyone been to a birthday party where there was no food and nothing to drink?

In the speech read by the General Manager of the hotel (the highlight of the program), I learned that the birthday date was actually the following week, but everyone would be busy hosting the Clintons and heads of state so this was really a pre-birthday program. It is true that this hotel regularly hosts movie stars and government bigwigs as well as the hoi polloi who come to New York for conventions and sales calls. The hotel claims high occupancy and advertises high room rates (standard rooms start at US$329 and club rooms begin at US$699 per night). Do not forget to add US$14.95 per day for a Wi-Fi fee. With these rates, high occupancy and Wi-Fi fees, I thought there would be enough money in the till to put on a good party; it appears that I was wrong.

Clues
If I had not been caught up with the fantasy of sipping a glass of chilled champagne while munching on a large succulent shrimp in mid-afternoon, I would have zoned in on the early warning signs of an approaching disaster. First of all, this is not a hotel noted for its restaurants, bars, coffee shops, or catered affairs. This is first and foremost a commercial property. It is definitely my fault that I did not fully register the pervasive smell of McDonald?s fries and Big Macs in the lobby that grabbed my nose as I entered the hotel lobby. Any hotel that does not flush food aromas out of the public space is not looking to establish its competitive advantage as a gourmet dining establishment.

Rushing through the lobby, I passed the check-in counter (looked more like an airport check-in than a hotel portal) and I kept walking until I finally spotted a small cluster of people lingering behind a small red-roped area. Was this birthday-party central I asked. ?Yes.?

I did a quick scan of the small space at the tail-end of the hotel lobby and wondered where the party guests were located. Where were the decorations, the bar and the food? Maybe, I thought optimistically, the guests were being held in the lobby, because the party room set-up was not completed. Perhaps it was more efficient to gather everyone in the lobby.

Sadly, what I saw ? was all there was - nothing but a large flat cake with Happy Birthday scripted in frosting.

Since I was really thirsty (and hungry from inhaling the Mickey D aroma) ? I asked for a glass of wine or a Diet Coke, PLEASE! ?No!? The only thing I could have was a seat! So I sat and waited for the program to begin.

Although I arrived on time, the program was to be delayed. Once again I gave the organization the benefit of the doubt! The goodies were going to be wheeled in, along with the party hats and favors and maybe a clown or two. Wrong again.

When a Birthday Bash includes a Speech
The ?party? started with a speech read by the General Manager and was followed by the identification of three employees who had spent 50 years of their lives with the hotel. The next low-keyed OMG was the acknowledgement of a food and beverage staffer who had carved a replica of the hotel in wax. This big project was followed by a round of applause for the Chef and welcome remarks by a representative from the Office of the Mayor who read parts of the Proclamation from the City of New York. The event ended with a bit of cake and a small bottle of water for the media, NYC and Co representatives, and assorted hotel employees.

What Next?
For those of us with a need to find a story, the public relations staff offered a tour of the newly-renovated rooms. I was motivated to join the group when I spied one of the staffers with a frosty cup of iced Starbucks coffee. I thought that if I went for the tour my reward would be an iced beverage; once again I was disappointed. Even when we visited the Executive Lounge where beverages were available for the guests, there was nothing for me!

So, What is New?
There might be renovated bathrooms, but shower curtains and no-name amenities make the space less than wonderful. The new window treatments and wall-to-wall carpet provide an aroma that might be classified as toxic for people with allergies; however, I am not a scientist so this is purely conjecture. What I do know is that I got a headache as soon as I entered the rooms and took a deep breath. The Executive Lounge is quite comfortable, and we spotted one guest sprawled out on a couch watching television. Clearly the fellow was at ease ? he was tall and the couch was long enough for him to stretch out, full-length.

We took a tour of the Health Club that is located on a level below-ground level. There may be a fee to use the machines; the costs are based on accommodations reserved. The space hosts a series rooms with a variety of machines plus an exercise room that could also be used as a closet if storage becomes a problem. An attractive display of guest towels was perhaps the highlight of this part of the tour.

A-List
This week the Clinton?s, the President of Egypt, and other senior-level executives and politicos will be staying at the hotel. I spotted lots of exposed wires (that looked like a safety hazard to me), but I was told that the electricians were setting up systems to cover the event.

This is also the ?real? week for the hotel?s birthday. Perhaps the former President, his wife and others who are A-listed will be treated to a real birthday party. I hope they will have a glass of champagne for me.

Source: http://www.eturbonews.com/31311/when-birthday-party-not-party

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?Luther? earned nominations for Best Movie/Miniseries and Best Actor in a Movie/Miniseries.

It?s become an annual tradition: Anglophenia?s live tweets of the Primetime Emmys. Follow us tonight starting at 7 pm ET for witty commentary and updates on the winners. BBC AMERICA boasts a record five nominations this year, including Best Miniseries for Luther and Best Actor in a Miniseries or TV Movie for star Idris Elba. Meanwhile, Downton Abbey was rewarded for its switch from the Miniseries to the competitive Drama categories with 16 nominations, and Sherlock: A Scandal in Belgravia has 13 nominations, including nods for stars Benedict Cumberbatch and Martin Freeman and writer Steven Moffat (Doctor Who).

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